HIV Prevention Services: PEP & PrEP
Protecting your health with fast, confidential, and effective prevention options.
Understanding PEP (Post-Exposure Prophylaxis)
What Is PEP?
PEP is an emergency HIV prevention medication taken after a possible exposure. It helps reduce the chance of acquiring HIV if started promptly.
When Should I Seek PEP?
Get PEP immediately if you think you were exposed to HIV.
You can obtain PEP from:
- Emergency Departments
- Urgent Care Clinics
- PrEP/PEP Navigators
- Sexual Health Clinics
PEP must be started within 72 hours. Every hour counts.
How PEP Works
- A provider evaluates your exposure.
- Treatment typically lasts 28 days.
- Follow-up HIV testing is required after completing the regimen.
Types of PEP: Occupational & Non-Occupational
Occupational PEP (oPEP)
For exposures that happen in the workplace, such as needle sticks or contact with infectious fluids in healthcare settings.
Non-Occupational PEP (nPEP)
For exposures that happen outside the workplace, including:
- Sexual exposure
- Sexual assault
- Sharing needles or injection equipment
Both forms follow similar treatment pathways but may differ in reporting and follow-up protocols.
Understanding PrEP (Pre-Exposure Prophylaxis)
What Is PrEP?
PrEP is a powerful strategy for people who want ongoing protection from HIV. When taken as prescribed, PrEP drastically reduces the risk of HIV transmission.
Available Options for PrEP
There are several PrEP options available today. Speak with your healthcare provider about what option is right for you.
- Daily PrEP Pills
- Every-two-month injectable PrEP
- Every-six-month injectable PrEP
Why Use PrEP?
PrEP is a part of a holistic prevention plan and works well alongside:
- Condom use
- Regular STI screening
- Contraceptive options
- Safer injection practices
Is PrEP Right for You?
PrEP may be helpful if you:
- Have a sex partner that is HIV positive
- Have multiple sex partners, or a partner with multiple sex partners
- Have anal sex without a condom
- Do not always use a condom during sex with people who inject drugs, men who have sex with men or a sex partner with unknown HIV status
- Have recently had a STD/STI in last 6 months
You use injection drugs, AND…
- Shared needles or equipment used to inject drugs in last 6 months
- Have been in drug treatment in the last 6 months
- Identify with any of the additional items listed above
Choosing Between PEP and PrEP
| If This Applies to You… | You Probably Need… |
|---|---|
| You Had a recent HIV exposure (within 72 hours) | PEP |
| You want ongoing protection | PrEP |
| You’re unsure what you need | Talk to your provider or a navigator |
Talk to your healthcare provider if you think PrEP is right for you. PrEP can be prescribed by any healthcare provider who is licensed to write prescriptions. Most insurance plans and state Medicaid cover PrEP. PrEP Access program can also help clients access PrEP services at no cost to them.
How to Access Services
Speak to a PrEP/PEP Navigator
Navigators help with:
- Confidential consultations
- Screening for eligibility
- Insurance and payment assistance
- Scheduling appointments
- Linkage to care and prevention services
Find PEP/PrEP Services Near You
PrEP and PEP services are available across Oklahoma through trusted community partners and other organizations dedicated to providing confidential and accessible HIV prevention support.
PrEP Access Programs
PrEP Access Programs operate in two regions of the state to ensure statewide coverage:
- H.O.P.E Tulsa – Serving individuals in the eastern region of Oklahoma
- PrEP/PEP Line: 918-416-0577
- Hours:
- Mon & Thurs – 9 am to 7 pm
- Tues & Wed – 9 am to 5 pm
- Fri & Sat – 9 am to 1 pm
- H.O.P.E will return all messages within 1 hour for PEP and 2 hours for PrEP
- Guiding Right, Inc. (GRI) – Serving individuals in the western region of Oklahoma
Both programs offer:
- PrEP/PEP navigation
- HIV and STI testing
- Prevention education
- Same-day PrEP and PEP initiation when available
- PrEP/PEP Hotline
Additional Navigation Support
The Southern Plains Tribal Health Board also provides PrEP/PEP navigation services to anyone in Oklahoma seeking support.
To connect with a navigator, text “Native PrEP” to 55251 to start a confidential chat. You can also visit their website for more information.